INVESTIGADORES
GARGIULO MONACHELLI Gisella Mariana
artículos
Título:
Long-term survival analysis of masitinib in amyotrophic lateral sclerosis
Autor/es:
MORA, JESUS S.; BRADLEY, WALTER G.; CHAVERRI, DELIA; HERNÁNDEZ-BARRAL, MARÍA; MASCIAS, JAVIER; GAMEZ, JOSEP; GARGIULO-MONACHELLI, GISELLA M.; MOUSSY, ALAIN; MANSFIELD, COLIN D.; HERMINE, OLIVIER; LUDOLPH, ALBERT C.
Revista:
Therapeutic Advances in Neurological Disorders
Editorial:
SAGE Publications Ltd
Referencias:
Año: 2021 vol. 14
ISSN:
1756-2856
Resumen:
Background: A randomized, placebo-controlled phase III study (AB10015) previously demonstrated that orally administered masitinib (4.5 mg/kg/day) slowed rate of functional decline, with acceptable safety, in amyotrophic lateral sclerosis (ALS) patients having an ALS Functional Rating Scale-revised (ALSFRS-R) progression rate from disease onset to baseline of