INVESTIGADORES
MUÑOZ Sonia Edith
artículos
Título:
Proaggregating and procoagulant properties of three murine mammary gland tumor cells.
Autor/es:
PASQUALINI, ME; RUIZ MORENO, L; MUÑOZ, SE; EYNARD, AR
Revista:
Experimental Toxicology and Pathology
Editorial:
Urban and Fisher
Referencias:
Año: 1997 vol. 49 p. 403 - 407
ISSN:
0940 2993
Resumen:
We have investigated the in vitro proaggregatory and procoagulant properties of three murine tumor cell lines having different metastatic potentials. The characterization was carried out with appropiate procoagulant inhibitors and plasma deficient in factors VII and X.
The proaggregatory properties of M2, M3 and MM3 cell lines increased according to their metastatic potentials. Their procoagulant activity were dependent on factor X. The prothrombotic abilities exhibited by neoplastic cells (NC), acting synergistically, might play a role in cancer dissemination
