Circulation of human coronaviruses OC43 and 229E in Córdoba, Argentina

OTOGALLI ME.; RODRIGUEZ, PE; FRUTOS, MC; MORENO L; GHIETTO LM; CUFFINI C; CAMARA, J; ADAMO P; VALINOTTO L; CAMARA, ALICIA

ARCHIVES OF VIROLOGY

SPRINGER WIEN

Año: 2021 p. 926 - 933

0304-8608

This is the frst study of respiratory infections in Córdoba, Argentina, caused by endemic human coronavirus (HCoV)-OC43and HCOV-229E, which circulated during 2011-2012 at a 3% rate, either as single or multiple infections. They were detectedmainly in children, but HCoV-229E was also found in adults. HCoV-229E was detected in fve out of 631 samples (0.8%),and HCoV-OC43 was found in 14 out of 631 (2.2%) samples. Clinical manifestations ranged from fever to respiratory distress, and a signifcant association of HCoV-229E with asthma was observed. Further studies and surveillance are neededto provide better clinical insights, early diagnosis, and medical care of patients, as well as to contribute to epidemiologymodeling and prevention.