INVESTIGADORES
BARI sara Elizabeth
artículos
Título:
In Vivo Studies of Hepatobiliary Excretion of Bilirubins.
Autor/es:
MORA, MARÍA EUGENIA; BARI, SARA E.; AWRUCH, JOSEFINA
Revista:
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
Editorial:
PERGAMON-ELSEVIER SCIENCE LTD
Referencias:
Lugar: Amsterdam; Año: 1997 vol. 7 p. 1249 - 1254
ISSN:
0960-894X
Resumen:
Hepatic metabolism of synthetic biliverdins 18-ethyl-1,19,21,24-tetrahydro-2,8,13,17- tetramethyl-1,19-dioxobilin-3,7,12- tripropionic acid (6) and coprobiliverdin II beta (7)- substrates in vitro of biliverdin reductase- showed that increasing hydrophilicity of bilirubins leads to their biliary excretion without conjugation.
