The flavonoid Salvigenin is active against Trypanosoma cruzi epimastigotes

CANO R, ; SPINA R, ; CIFUENTE DA; BARRERA P, ; SOSA MA, ; LOZANO E.

Merlo-San Luis

Congreso; XXXV Reunión Científica Anual de la Sociedad de Biología de Cuyo.; 2017

Trypanosoma cruzi is the etiological agent of chagas? disease. In cultures, these parasites cycle between the flagellate epimastigote form, and scarcely they differentiate into the infective trypomastigote. Natural compounds extracted from plants have shown to be effective against the parasite. Among them, flavonoids are an important family of natural compounds largerly studied. In this study, a novel flavone, Salvigenin (SVG), purified from aerial parts of Baccharis scandens, has been evaluated on T. cruzi growth.