CHARACTERIZATION OF THE PRECURSOR ENCODING FOR GNIH AND IMMUNOHISTOCHEMICAL LOCATION OF THIS PEPTIDE IN THE BRAIN OF ODONTESTHES BONAERIENSIS (ATHERINIFORMES).

PAHÍ-ROSERO ANA M.; PÉREZ MARÍA R.; MECHALY ALEJANDRO S.; LÓPEZ GABRIELA C.; ORTÍ GUILLERMO; VISSIO PAULA G.; SOMOZA GUSTAVO M.

Manaos

Congreso; 11th International Symposium on Reproductive Physiology of Fish; 2018

Gonadotropin-inhibitory hormone (GnIH) is a member of the RFamide neuropeptide family, originally discovered and characterized in birds. It is known that this peptide is involved in the inhibition of gonadotropin release from the pituitary of birds and mammals, however its function in teleosts has not been clearly established. Pejerrey, Odontesthes bonaeriensis, is a native fish from continental waters of the Pampas region of Argentina and has been used as a model for research on reproduction and sex differentiation. In view of the diverse mechanisms involved in the hypothalamic control of pituitary function in fish, and due to the scarce information of GnIH physiology in teleosts, we performed an in silico analysis of the GnIH precursor sequence and its position in a GnIH phylogenetic tree, along with the study of its brain-pituitary distribution.