INVESTIGADORES
FUSCO luciano Sebastian
artículos
Título:
"VENOMS AND ISOLATED TOXINS FROM SNAKES OF MEDICAL IMPACT IN THE NORTHEAST ARGENTINA: STATE OF THE ART. POTENTIAL PHARMACOLOGICAL APPLICATIONS."
Autor/es:
DENEGRI EMILIA; BUSTILLO SOLEDAD; PAMELA TEIBLER; MATIAS SANCHES; FABIAN BOGADO; GAY C.; ECHEVERRÍA S.M.; FUSCO LUCIANO SEBATIAN; LAURA LEIVA
Revista:
Current Topics in Medicinal Chemistry
Editorial:
BENTHAM SCIENCE PUBL LTD
Referencias:
Año: 2019
ISSN:
1568-0266
Resumen:
Abstract: Among the ophidians that inhabit the Northeast of Argentina, the genus Bothrops such as B.alternatus and B. diporus species (also known as yararás) and Crotalus durisus terrificus (named cascabel),represent the most studied snake venom for more than thirty years. These two genera of venomoussnakes account for the majority of poisonous snake envenomations and therefore, constitute a medicalemergency in this region. This review presents a broad description of the compiled knowledge aboutvenomous snakebite: its pathophysiological action, protein composition, isolated toxins, toxin synergism,toxin-antitoxin cross-reaction assays. Properties of some isolated toxins support a potential pharmacologicalapplication.
