Zn-limited diet modifies the expression of the rate-regulatory enzymes involved in phosphatidylcholine and cholesterol synthesis

GOMEZ NN; BIAGGIO VS; ROZZEN E; ALVAREZ SM; GIMENEZ, MS

BRITISH JOURNAL OF NUTRITION

Published on behalf of the Nutrition Society by CABI Publishing

Lugar: Inglaterra; Año: 2006 p. 1038 - 1046

0007-1145

Suboptimal intake of Zn is one of the most common nutritional worldwide problems. Previously, we showed that Zn deficiency produces alterations in lung lipid metabolism in rats. We studied the effect of a Zn-limited (ZL) diet on the expression of the enzymes involved in phosphatidylcholine and cholesterol synthesis. After 2 months of treatment with a ZL diet we found important variations in the lipid content of Wistar male rats: triacylglycerol (TG) decreased 60% (P