Multilobe morphology: the secret of biphasic nanogels for dual-task

ANA SONZOGNI; VERÓNICA GONZALEZ; ROQUE MINARI

Simposio; Virtual International Symposium on Nano and Microgels; 2020

Polymat

n the case of nanogels (NGs), numerous synthesis strategies were implemented to expand NGs properties by adding different functionalities, inorganic compounds or natural polymers. However, the synthesis of two-phase polymer-polymer NGs which expanded functionalities has not been highly exploited. Recently, we reported the synthesis of biphasic NGs based on poly(Nvinylcaprolactam) (PVCL) by semibatch strategy in one pot [1]. This system offers the opportunity of combining the high loading capacity and thermoresponsivity of NGs with the delivery capability and occlusion effect obtained from a macro-film platform, which could be previously formed or directly casted onto the surface where the release is required (i.e., in situ formed).In this talk I will present the particle formation process of these multilobed NGs, and discussed the formation mechanism on the basis of the model reported by Blenner et al.