Room-Temperature and Transition-Metal-Free Mizoroki Heck-type Reaction. Synthesis of E-Stilbenes by Photoinduced C H Functionalization

GUASTAVINO, JAVIER F.; BUDÉN, MARÍA E.; ROSSI, ROBERTO A.

JOURNAL OF ORGANIC CHEMISTRY

AMER CHEMICAL SOC

Lugar: Washington; Año: 2014 vol. 79 p. 9104 - 9111

0022-3263

We report a conceptually different approach toward E-stilbene syntheses by photoinduced direct C H arylation of alkenes at rt without the addition of transition metals, with a broad range of aryl halides, including ArI, ArBr, and even ArCl. This is the first time that this reaction has been produced without extra solvent but with 18-crown-6 ether and t-BuOK in only 15 min of reaction