INVESTIGADORES
ROMANELLI Gustavo Pablo
artículos
Título:
Wells-Dawson Type Catalyst: An Efficient, Recoverable and Reusable Solid Acid Catalyst for the Solvent-Free Synthesis of Benzodiazepines
Autor/es:
G. PASQUALE; D. RUIZ; G. BARONETTI; H. THOMAS; J. AUTINO; G. ROMANELLI
Revista:
Current Catalysts
Editorial:
Bentham
Referencias:
Año: 2014 vol. 3 p. 229 - 233
ISSN:
2211-5447
Resumen:
Various 3-H-1,5-benzodiazepines were prepared from the solvent-free reaction of o-phenylenediamine and substituted 1,3-diphenyl-1,3-propanedione, giving good yields of benzodiazepines. The H6P2W18O62.24H2O solid heteropolyacid, which has a Wells-Dawson type structure was used as catalyst both in bulk and silica-supported forms (0.1, 0.2, 0.4 and 0.6 g/g, named 0.1WDSiO2, 0.2WDSiO2, 0.4WDSiO2 and 0.6WDSiO2, respectively). The structure of the synthesized heteropolyacid was confirmed using different characterization techniques (FTIR; 31P-RMN, and potentiometric titration).
