INVESTIGADORES
ROMANELLI Gustavo Pablo
artículos
Título:
Efficient method for tetrahydropyranylation depyranylation of phenols and alcohols using solid acid catalyst with Wells-Dawson structure
Autor/es:
G. P. ROMANELLI; GRACIELA BARONETTI; HORACIO J. THOMAS; JUAN C. AUTINO
Revista:
TETRAHEDRON LETTERS
Editorial:
PERGAMON-ELSEVIER SCIENCE LTD
Referencias:
Lugar: Amsterdam; Año: 2002 vol. 43 p. 7589 - 7591
ISSN:
0040-4039
Resumen:
A simple and efficient procedure to form 2-tetrahydropyranyl acetals of phenols and alcohols is reported. Wells?Dawson heteropolyacid catalyst is used both in bulk form or supported on silica, reaction conditions include room temperature and toluene as solvent. Fast deprotection of THP-acetals can be attained by mere change of the solvent using THF?1% MeOH. In both reactions the supported catalyst is easily recoverable and reusable, and the yields are good to excellent.
