Our experience in stereoelectroencephalography and electrical stimulation in a public hospita

NASIMBERA, A. H; GIAGANTE, BRENDA; ODDO, SILVIA; SILVIA KOCHEN

Bangkok

Congreso; 33rd International Epilepsy Congress; 2019

ILAE - INTERNATIONAL LEAGUE AGAINST EPILEPSY

RATIONALEStereo-electroencephalography (SEEG) is a procedure conducted in patients with intractable epilepsy in order toanatomically define the epileptogenic zone (EZ) and the possible related functional cortical areas. Electrical stimulation(ES) was developed to accurately identify cortical structures essential to language and motor function, and to triggerseizures. The aim of this study is to analyze SEEG and electrical stimulation (ES) findings in our patient populationMETHODSWe analyzed 30 patients with drug resistant epilepsy from our Video-EEG unit who underwent a SEEG as part of a surgicalplan. During SEEG, bipolar stimulation using low frequency (typically 1 Hz) or high frequency stimulations (typically 50 Hzduring 5 s) were used to map functional cortex or to trigger seizures. Stimulations was usually performed having alreadyrecorded spontaneous seizures. Electrical stimulation was stopped when a seizure was induced or an after discharge waspresent on the EEG recording. Cognitive tasks performed during ES were: hand tapping, naming, automatic speech(counting, familiar lines, reciting), reading and verbal fluency.CONCLUSIONSThis procedure allowed us to accurately locate the EZ, to identify the temporal-space dynamics of the epileptogenicnetwork and the to perform a functional mapping of the cortex in order to plan cortical resections without overlapping, thus,improving surgical prognosis. Even though postsurgical prognosis in patients in which the EZ involves eloquent areas ispoor , preserving functional areas could also improve quality of life.