Biomarkers of endothelial dysfunction in relation to nutrition

DEFAGÓ MD; MARCHIORI GN

Biomarkers in Disease: Methods, Discoveries and Applications

Springer Nature

Año: 2022; p. 1 - 500

Endothelial dysfunction is a term that covers diminished production and availability of nitric oxide as well as an imbalance in the relative contribution of endothelium-derived relaxing and contracting factors. It is a leading cause of cardiovascular disease (CVD), and it can be considered a marker of risk and a prognostic marker.Several epidemiological studies have shown that adherence to a healthy diet pattern is associated with a reduction in the incidence of CVD and an improvement in plasma concentrations of biomarkers of endothelial dysfunction. This chapter reviews the evidence about endothelial biomarkers and their relationship to adherence to dietary patterns and specific nutrient intake.