BECAS
ORTIZ MOYANO Francisco Ramiro
congresos y reuniones científicas
Título:
Postimmunobiotics increase antiviral immunity in alveolar macrophages: impact on the resistance against respiratory syncytial virus.
Autor/es:
RAYA TONETTI, FERNANDA; ORTIZ MOYANO, RAMIRO; MAIDANA, STEFANIA DENTICE; ELEAN, MARIANO; VILLENA, JULIO
Lugar:
Mar del Plata
Reunión:
Congreso; LXX Reunión científica anual de la Sociedad Argentina de Inmunología; 2022
Institución organizadora:
Sociedad Argentina de Inmunología
Resumen:
Beneficial microbes with immunomodulatory capacities (immunobiotics) and their nonviable forms (postimmunobiotics) could be effectively utilized in formulations for the prevention ofrespiratory viral infections. In this study, novel immunobiotic strains with the ability to increase antiviral immunity in porcine alveolar macrophages were selected from a library of Lactobacillusgasseri. Postimmunobiotics derived from the most remarkable strains were also evaluated in their capacity to modulate the immune response triggered by Toll-like receptor 3 (TLR3) inalveolar macrophages and to differentially regulate TLR3-mediated antiviral respiratory immunity in infant mice.
