Bacillus subtilis a novel probiotic to improve innate immunity and host health parameters

ARGAÑARAZ, FEDERICO; MÁRQUEZ, ANTONELA; BAUMAN, CARLOS; GAUFFIN-CANO, PAOLA; GRAU, ROBERTO

Congreso; XII Congress of the Latin American Association of Immunology; 2018

Introduction: Bacillus subtilis is a Gram-positive spore-forming bacterium that is recognized as a probiotic organism. Probiotics are live organisms that have a beneficial effect on host health when they are administered or present in adequate quantities. Spores of B. subtilis are very resistant to extreme environmental conditions, including heat, desiccation and extreme pH, and thus allows the bacteria to survive the transit through the gastrointestinal tract of animals and humans. One global health problem of society concern is the actual epidemic of obesity.Objective: The aim of this work was determine if the administration of Bacillus subtilis improves the immunologic and metabolic parameters in normal mice as well as in a fat mice model.