INVESTIGADORES
BRACAMONTE Angel Guillermo
artículos
Título:
Development of a polymeric nanobiosensor for fast and PCR-free genotyping applications
Autor/es:
DANNY BROUARD, OLIVIER RATELLE, ANGEL GUILLERMO BRACAMONTE, FÉLIX-ANTOINE LAVOIE, MARYSE ST-LOUIS, DENIS BOUDREAU
Revista:
ANALYST
Editorial:
ROYAL SOC CHEMISTRY
Referencias:
Lugar: CAMBRIDGE; Año: 2013 vol. 5 p. 6896 - 6899
ISSN:
0003-2654
Resumen:
A biosensor based on a cationic polymer and metal@silica core-shell nanoparticles is demonstrated for the rapid identification of the SRY gene from unamplified human genomic DNA. By amplifying the fluorescence signal triggered by the capture of target molecules, this biosensor avoids the added complexity of enzyme-based chemical amplification, makes genotyping assays faster and less costly and could have important applications in various areas of health sciences.