Generation of Bioimaging towards design of hybrid micro-machines and micro-swimmers

LUNA R. GOMEZ-PALACIOS; A. GUILLERMO BRACAMONTE

J. Chem. Research Adv.

Open Access (CC) Creative Commons Attribution

Año: 2022 vol. 3 p. 22 - 27

In this brief review we analyze a current trend within photochemistry and photobiology related to nano-biolabeling of different biostructures such as unicellular micro-organisms, bacteria, and viruses for early detection and diagnosis by Enhanced Bioimaging, within In Flow detection and counting. By this way, it could be analyzed single Biostructure as well as aggregates in higher concentrations. Nano-labellers could show variable emission properties depending on the intrinsic matter constitution of the designed nano-particle. The composition could incorporate varied non-classical light sources. Thus, the study of metal-enhanced fluorescence (MEF), fluorescence resonance energy transfer (FRET), coupled phenomena, and other enhanced scattering light phenomena is highlighted. We discuss the deposition of nano-emitters on biostructures for targeted studies and specific applications. And in this context recently, it was reported different designs of nano-emitters for the generation of ultraluminescent biostructures, single biostructure detection, targeted light delivery through biostructures, and other applications as protection agents against antibiotics and stabilizing agents of nano-vaccines. In addition, from these studies and applications, the perspectives of these nano-biostructures as synthetic or hybrid biostructures for targeted applications within biotechnology were discussed. In these synthetic Nano-Biostructures, each component acts as a functional component to generate the final function. Moreover, it was afforded to show and discuss about Dynamics of interactions between the different components of the hybrid structure and inter-Nano-Biostructure interactions to form Nano-Bio-assemblies for multiple uses Thus, the concept of micro-machines for nano-medicine and biotechnology was introduced. This short communication intends to show important research developments from fundamental studies towards targeted applications.