Differences in liver and peripheral blood phenotype of Natural Killer and T cells in healthy subjects

A. PODHORZER; A.P. MACHICOTE; S. MONTAL; S. MARCIANO; O. GALDAME; P. BAZ; S. BELEN; G. PODESTA; L. FAINBOIM

Congreso; LXIII Reunión Científica Anual de la Sociedad Argentina de Inmunología; 2015

Background: Most immunological studies on NK cells and T cells have focused onperipheral blood (PB) cells. The present study aimed to investigate the different NK and T cellphenotype obtained from PB, liver wedge biopsies (LWB) and liver perfusion (LP) MNCs from healthydonors (HD).Methods: NK receptors and T cells markers were analyzed by flow cytometry on PBMC´s from HD(N=63), LP collection (N=14) and LWB (N=22).Results: Liver resident NK cells show increased frequencies of NKbright 18.3% Vs 0.8 in PB;(p