Optimization of the subcritical water extraction of sulfated flavonoids from Flaveria bidentis

FALLETI PAULINA; BARRERA VAZQUEZ FERNANDA; GONÇALVES RODRIGUES L.G; SANTOS P.H.; LANZA M. ; CABRERA J. L.; MARTINI R.; COMINI LAURA R. (CORRESPONDING AUTHOR)

JOURNAL OF SUPERCRITICAL FLUIDS

ELSEVIER SCIENCE BV

Lugar: Amsterdam; Año: 2023

0896-8446

Flaveria bidentis, an invasive plant, contains sulfated flavonoids (SFs) with therapeutic potential; therefore, their extraction would add value to the plant residues generated during its weeding. This work reports the optimized obtaining of these SFs, by means of subcritical water extraction (SWE). The combined effects of Flow rate, Temperature, and Particle size were investigated via response surface methodology involving the Doehlert experimental design. The optimal extraction conditions were: leaves: Flow rate = 2.86 mL/min, Temperature = 101.2 °C and Particle size = 420–