INVESTIGADORES
LEON Ignacio Esteban
artículos
Título:
Bis(oxalato)dioxovanadate(V) and bis(oxalato)oxoperoxo- vanadate(V) complexes: Spectroscopic characterization and biological activity
Autor/es:
LEON I.E, ETCHEVERRY S.B., PARAJÓN-COSTA B.S., BARAN E.J.ETCHEVERRY S.B; ETCHEVERRY S.B; PARAJÓN-COSTA B.S.; BARAN E.J
Revista:
BIOLOGICAL TRACE ELEMENT RESEARCH
Editorial:
HUMANA PRESS INC
Referencias:
Lugar: Oregon; Año: 2013 p. 295 - 300
ISSN:
0163-4984
Resumen:
Two structurally related vanadium(V) complexes, K3[VO2(C2O4)2]·3H2O and K3[VO(O2)(C2O4)2]·1/2H2O, were thoroughly characterized by infrared, Raman, and electronic spectroscopies. The effect of both complexes on the viability of the human MG-63 osteosarcoma cells was tested using the MTTassay. The monoperoxo complex shows a very strong antiproliferative activity (at 100-μMconcentration, this complex diminished the cell viability ca. 80 %), whereas the dioxo complex was inactive.
