PERSONAL DE APOYO
TORRES CARRO Romina
artículos
Título:
Effect of wine wastes extracts on the viability and biofilm formation of Pseudomonas aeruginosa and Staphylococcus aureus strains
Autor/es:
VIOLA, C.M.; TORRES CARRO, R.; CARTAGENA, E.; ISLA, M.I.; ALBERTO, M.R.; ARENA, M.E.
Revista:
EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE
Editorial:
OXFORD UNIV PRESS
Referencias:
Lugar: Oxford; Año: 2018 vol. 2018 p. 1 - 9
ISSN:
1741-427X
Resumen:
ACLARACIÓN: Como se aclara al final del manuscrito final, la primera autoría es compartida por las licenciadas Romina Torres Carro y Carolina Viola, a pesar de lo establecido en el orden de autores.//////In this work, we intended to inhibit the biofilm synthesis and the metabolism of Gram positive and Gram negative bacteria using two highly available wastes (stem and marc) obtained after the manufacturing of Torrontes wine at Cafayate, Argentina. Wine wastes contains a significant amount of bioactive compounds, mainly phenolic compounds, which makes them a potential source of compounds with beneficial properties to human health, as they could inhibit the virulence of pathogenic bacteria or protect the tissue against oxidative stress. Marc and stem extracts of Torrontes wine were evaluated for their ability to inhibit the metabolism and biofilm production of Pseudomonas aeruginosa and Staphylococcus aureus strains. The phytochemical composition and antioxidant activity of these extracts were also determined. The methanol and ethyl acetate extracts, which contained the highest amount of total polyphenolic, exhibited the highest scavenging capacity of ABTS and nitric oxide, and the strongest Fe3+ reducing power; as well as exhibited the highest level of inhibition of the biofilm formation and of the metabolic activity in bacterial biofilm. We also noticed a positive correlation between phenolic compounds content, the antioxidant activity and the anti-biofilm capacity of the winemaking wastes. These results display the potentiality of wine wastes to prevent or reduce the formation of biofilm. Moreover, their abundance makes them an attractive and affordable source of anti-biofilm and antioxidant agents.
