Anti-fungal and anti-allergic effects of achyrocline satureioides flowers decoction

ALANIZ F; ANDRADA M; GIORDANA M; GONZALEZ PEREYRA ML; DEMO M; CARIDDI LN; MALDONADO AM

Jornada; XVII Jornadas Científicas de la Sociedad de Biología de Córdoba; 2009

Achyrocline satureioides has been used in popular medicine by its anti-inflammatory properties. Objectives were to evaluate the effects of Achyrocline satureioides flowers decoction (FD) on basophils from allergic patients to environmental fungi and to investigate mycelia growth in cultures of isolated fungi from house of each. Prick test and enzyme β-hexosaminidase release (β-H) test from basophils challenged with the allergen were assayed. The basophils were challenged with the allergen alone (100 PNU/ml); or added of FD or antihistamine drugs. Aeroallergens fungi were isolated and identified by optical microscopy and characterized by sort. The anti-fungal effect of FD was determined on the growth of mycelia. The liberation of β-H was decreased by FD (optimal dose 4mcg/ml), p