Malassezia species associated to seborrhoeic dermatitis and atopic dermatitis

GIUSIANO G; SOSA MA; ROJAS F; MANGIATERRA M; CARRILLO MUÑOZ AJ; TOMA VANACORE S; DELUCA G

Torino, Italia

Congreso; 3rd Trends in Medical Mycology; 2007

Lipophilic yeast of genus Malassezia are considered as a normal inhabitants of the normal human skin and also implicated in the pathogenesis of various dermatoses with universal distribution such as seborrhoeic dermatitis (SD) and atopic dermatitis (AD). The relationship between the Malassezia species and skin diseased associated with them remains unclear. The frequency of Malassezia species observed differs from some studies reported by others authors. In this work M. globosa was the most frequent specie isolated in DS and AD, followed by M. furfur. It’s remarkable the isolation of 2 strains of the primary zoophylic M. pachydermatis from DA  and DS lesions.PCR-RFLP allowed the detection and characterization of Malassezia species mixtures, which are difficult to discriminate with other molecular techniques and almost impossible with conventional physiological and biochemical tests.M. globosa was isolated from all body sites studied. In AD M. furfur was is less frequent in face and neck. The role that each Malassezia species plays in several cutaneous disorders are under study. This is a contribution to the knowledge of Malassezia genus ecology.