Bioactive Composite Coatings Based On Poly(ɛ-caprolactone) Obtained By Electrophoretic Deposition

GISELA QUIROGA; MARIO NINAGO; MARIA J. SANTILLAN

Gyeongju

Conferencia; International Conferences on EPD; 2017

International Network EPD

Design and fabrication of bioactive polymeric materials for tissue engineering is an area of growing interest, particularly due to the wide range of opportunities that offer polymeric materials. Poly(ɛ-caprolactone) PCL, was synthetized by anionic polymerization techniques and chemically functionalized with maleic anhydride 3% (w/w). Modified PCL was used for the fabrication of a composite material with bioglass (BG) deposited on stainless steel through Electrophoretic Deposition (EPD) technique. Microstructural studies (FTIR and SEM) revealed the effectiveness of the modifier agent used, as well as a well distribution of bioglass particles on the composite coating. Finally, in vitro assays were carried by immersion on simulated body fluid solution for 14 days. SEM-EDX and XRD analyses confirmed the formation of a hydroxyapatite (HA) layer over PCL membrane after immersion in SBF solution, exhibiting Ca/P values ~ 1.98, being this value closer to ratio values observed for the HA in hard tissues.