INVESTIGADORES
RIUS Sebastian Pablo
artículos
Título:
Flavonoids: Biosynthesis, Biological functions and Biotechnological applications. Front. Plant Sci. 3:222. doi: 10.3389/fpls.2012.00222
Autor/es:
FALCONE FERREYRA, M.L.; RIUS, S.P.; CASATI, P.
Revista:
Front. Plant Sci.
Editorial:
Frontiers Editorial
Referencias:
Año: 2012 vol. 3 p. 1 - 15
ISSN:
1664-462X
Resumen:
Flavonoids are widely distributed secondary metabolites with different metabolic functions in plants. The elucidation of the biosynthetic pathways, as well as their regulation by MYB, bHLH and WD40-type transcription factors, has allowed metabolic engineering of plants through the manipulation of the different final products with valuable applications. The present review describes the regulation of flavonoid biosynthesis, as well as the biological functions of flavonoids in plants, such as in defense against UV-B radiation and pathogen infection, nodulation, pollen fertility. In addition, we discuss different strategies and achievements through the genetic engineering of flavonoid biosynthesis with implication in the industry and the combinatorial biosynthesis in microorganisms by the reconstruction of the pathway to obtain high amounts of specific compounds.
