IL-1b, IL-2, IL-4 and IL-10 profile during porcine gestation.

VELEZ, CAROLINA; WILLIAMSON, DELIA; KONCURAT, MIRTA

Puerto Varas

Congreso; Latin American Society for Maternal Fetal Interaction and Placenta (SLIMP), Sociedad Chilena de Ciencias Fisiológicas (SCHCF); 2017

Sociedad Chilena de Ciencias Fisiológicas

During gestation, a dialogue is carried out between the conceptus and the endometrium involving the immune system in order to minimize the embryo rejection probabilities. The porcine placenta is epitheliochorial, non-invasive, adecidua, folded, and diffuse. Objectives: Concentration of interleukins 1β (IL-1β), 2 (IL-2), 4 (IL-4), and 10 (IL-10) in serum from mother and porcine placental extracts from different gestation periods was determined. Methods: Crossbred female placental samples (n = 25) of 17, 30, 60, 70, and 114 days of gestation (dg) and non-pregnant uterus (n = 5) were used. Interleukins determination was performed by ELISA. Results: IL-1β, IL-2, and IL-4 showed two peaks of concentration at the placental interface (P