INVESTIGADORES
MARIÑO Karina Valeria
artículos
Título:
Facile synthesis of methyl alpha- and beta-D-[6-3H]galactofuranosides from D-galacturonic acid. Substrates for the detection of galactofuranosidases
Autor/es:
BORDONI, ANDREA; LIMA, CARLOS; MARIÑO, KARINA; LEDERKREMER, ROSA M. DE; MARINO, CARLA
Revista:
CARBOHYDRATE RESEARCH
Editorial:
ELSEVIER SCI LTD
Referencias:
Año: 2008 vol. 343 p. 1863 - 1869
ISSN:
0008-6215
Resumen:
Galactofuranose metabolism is a good target for the development of novel chemotherapeutic agents for the treatment of some microbial infections. A simple procedure for the synthesis of methyl (methyl alpha,beta-D-galactopyranosid)uronate followed by NaB3H4 reduction gave a straightforward access to radiolabeled substrates for galactofuranosidases.
