Polymeric microparticles as salicylic acid carriers

MERARI CHEVALIER; JIMENA SOLEDAD GONZALEZ; VERA ALEJANDRA ALVAREZ

Porto Galinhas

Simposio; XIV Latin American Symposium on Polymers (Simpósio Latino Americano de Polímeros ? SLAP); 2014

There are many disadvantages associated with the use of certain drugs. These are distributed in the organism according to their physical properties such as solubility, partition coefficient and charge. In consequence, drugs can reach a variety of sites where they are outside of their therapeutic range, where they are inactive, or where their action is unwanted or harmful and therefore with negative side effects. Therefore, therapeutically effective and patient-compliant drug delivery systems continuously lead researchers to design novel tools and strategies. . Polymers are the first choice to obtain drug-carriers because: Their stability and capability for high loading of many agents and their control over drug release kinetics and capability for modified their surface for attached ligands. This work attempts to study the behaviour of polymers as drug carriers synthesizing microparticles of PVA and PCL loaded with salicylic acid.