INVESTIGADORES
MENCHON Silvia Adriana
artículos
Título:
Ontogenetic growth of multicellular tumor spheroids
Autor/es:
CARLOS ALBERTO CONDAT; SILVIA ADRIANA MENCHÓN
Revista:
PHYSICA A - STATISTICAL AND THEORETICAL PHYSICS
Editorial:
Elsevier
Referencias:
Año: 2006 p. 76 - 79
ISSN:
0378-4371
Resumen:
In ontogenetic growth models, the basal metabolic rate is usually assumed to depend on the individual mass following a power law. Here it is shown that, in the case of multicellular tumor spheroids, the emergence of a necrotic core invalidates this assumption. The implications of this result for spheroid growth are discussed, and a procedure to determine the growth parameters using macroscopic measurements is proposed.
