INVESTIGADORES
FERRONATO Maria Julia
artículos
Título:
Synthesis and biological evaluation of a new vitamin D2 analogue
Autor/es:
GÁNDARA, Z.; PÉREZ, M.; SALOMÓN, D.G.; FERRONATO, M.J.; FERMENTO, M.E.; CURINO, A.C.; FACCHINETTI, M.M.; GÓMEZ, G.; FALL, Y.
Revista:
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
Editorial:
PERGAMON-ELSEVIER SCIENCE LTD
Referencias:
Año: 2012 vol. 22 p. 6276 - 6279
ISSN:
0960-894X
Resumen:
A new vitamin D2 analogue was synthesized using the Julia Kocienski olefination. It has antiproliferative effects on cell lines from squamous cell carcinomas of colon and head and neck, but is also as hypercalcaemic as calcitriol in vivo.
