A Compartive Study of Chemical versus Biological Functionalization of Synthetic Intermediates

ARSENIYADIS, S.; RODRIGUEZ, R.; BRONDI, R.; SPANEVELLO, R. A.

Microbial Reagents in Organic Synthesis

Kluwer Academic Publisher

Lugar: Sestri Levante; Año: 1992; p. 313 - 321

A combination of microbial hydroxyltion and lipase mediated hydrolysis insured access to chiral synthtetic intermediates whose relative inaccessibility by conventional chemical means is obvious. Examples are give for allylic hydroxylations with Rhizopus arrhizus and ester hydrolysis with lipases