Candida albicans activates the type I interferon pathway in cells of the female genital tract

RODRIGUEZ, E; VIGEZZI, CECILIA; ICELY, PA; SOTOMAYOR, CE

MAR DEL PLATA

Congreso; REUNION CONJUNTA SAIC SAI SAFIS 2018; 2018

SOCIEDAD ARGENTINA DE INMUNOLOGIA

C albicans ( is an opportunistic fungal pathogen that typically exists as aharmless commensal in the female genital tract however, approximately75 of women who are of reproductive age suffer from vulvovaginalcandidiasis ( at least once in their lifetime Besides a percentagebetween 6 and 8 experience recurrent episodes of VVC (characterized by at least four episodes of VVC per year Recent studiesrevealed that, besides viruses and bacteria, fungal pathogens can alsoinduce type I interferons (IFNs I) production by innate immune cells