CONICET | Buscador de Institutos y Recursos Humanos

Progress in Biomaterials now accepted for Science Citation Index Expanded (SCIE) - We are very happy to announce that Progress in Biomaterials has been accepted for the Science Citation Index Expanded and will get its first Impact Factor in 2022. All articles that have been published since 2019 will be indexed in Web of Science (please note that this process has not been finalized yet by Clarivate Analytics).Since surface plays a key role in bioactivity, the response of the host to the biomaterial will determine the success or failure of the prosthesis. The purpose of this study is to make an exhaustive analysis of the histological and histochemical characteristics of new bone tissue around Zr implants anodized at 60 V (Zr60) supported by histomorphometric methods in a rat model. Fibrous tissue was observed around the control implants (Zr0) and osteoblasts were identifed on the trabeculae close to the implantation site that showed typical cytological characteristics of active secretory cells, regardless of the surfacecondition. The histomorphometrical analysis revealed a signifcant increase in cancellous bone volume, trabecular thickness and in trabecular number together with a decrease in trabecular separation facing Zr60. TRAP staining showed that there was a relative increase in the number of osteoclasts for Zr60. In addition, a larger number of osteoclast with a greater number of nuclei were detected in the tibiae for Zr60. This research demonstrated that the new bone microarchitecture in contact with Zr60 is able to improve the early stages of the osseointegration process and consequently the primary stability of implantswhich is a crucial factor to reduce recovery time for patients.

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