PERSONAL DE APOYO
QUASSOLLO INFANZON Gonzalo Emiliano
congresos y reuniones científicas
Título:
Cdc42 is a master regulator of mitochondrial fission.
Autor/es:
ZAMPONI EMILIANO; ZAMPONI, NAHUEL; QUASSOLLO, GONZALO; HELGUERA, PABLO
Reunión:
Simposio; Cell Symposium: Multifaceted Mitochondria.; 2018
Resumen:
Mitochondrial fission is essential for proper organelle localization andfollowing ER-mitochondria contact, INF2-dependent actin polymerizationSubsequent assemble of Drp1 rings around constricted mitochondrionallowing Dyn2 to achieve mitochondrial scission. However, neither theregulatory pathways governing these processes have been elucidated. Recent studies have shown thatpromotes mitochondrial constriction in situ.ensures the decrease of tubule diameter,specific actin structures implicated nor the