INVESTIGADORES
GRUBER Nadia
artículos
Título:
An efficient synthesis of N-alkyl-N-arylputrescines and cadaverines
Autor/es:
MARÍA C. MOLLO; NADIA GRUBER; JIMENA E. DÍAZ; JUAN A. BISCEGLIA; LILIANA R. ORELLI
Revista:
ORGANIC PREPARATIONS AND PROCEDURES INTERNATIONAL
Editorial:
ROUTLEDGE JOURNALS, TAYLOR & FRANCIS LTD
Referencias:
Lugar: Londres; Año: 2014 vol. 46 p. 444 - 452
ISSN:
0030-4948
Resumen:
This work describes a practical method for the synthesis of tertiary N-alkyl-N-aryltetra- and pentamethylenediamines 3, by selective monoalkylation of N-alkylanilines with ω−haloalkylnitriles followed by reduction. The optimized reaction conditions resulted in an efficient procedure, of remarkable selectivity in the alkylation step and high overall yields of the diamines.
