INVESTIGADORES
FERNANDEZ Mariela Alejandra
artículos
Título:
Antimicrobial activities of bacterial cellulose ? Silver montmorillonite nanocomposites for wound healing
Autor/es:
MANUEL, HORUE; MAXIMILIANO L. CACICEDO; MARIELA A. FERNANDEZ; BORIS RODENAK-KLADNIEW; ROSA M. TORRES SÁNCHEZ; GUILLERMO RAÚL CASTRO
Revista:
MATERIALS SCIENCE & ENGINEERING. C, BIOMIMETIC MATERIALS, SENSORS AND SYSTEMS
Editorial:
ELSEVIER SCIENCE BV
Referencias:
Lugar: Amsterdam; Año: 2020
ISSN:
0928-4931
Resumen:
A nanocomposite based on bacterial cellulose (BC) containing montmorillonite (MMT) modifiedwith silver (BC-MMT-Ag) was developed to be used as potential scaffold for wound healing.Montmorillonite was suspended in silver nitrate solution to incorporate silver in the matrix by ionexchange. The derivative silver clay suspension was used to modify bacterial cellulose membranes by ex situ technique. The BC nanocomposite was analyzed by thermal analysis, scanning electronmicroscopy, Fourier transform infrared and electron dispersion spectroscopies, X -ray diffraction, and rehydration capacity . The antimicrobial activity of the silver montmorillonite-bacterial cellulose nanocomposite was challenged in cultures of Gram(+) Staphylococcus aureus and Gram( -) Pseudomonas aeruginosa, and showed inhibition of growth in agar plates and biofilm formation as revealed by live -dead assay . Cytotoxicity of BC nanocomposites containing 1% to 25% of MMT -Ag showed good in vitro biocompatibility with L929 fibroblast cells.
