In-phantom dosimetry for boron neutron therapy (BNCT)

G. GAMBARINI V. COLLI S. GAY C. PETROVICH G. ROSI M. VALENTE

5th INTERNATIONAL CONFERENCE ON ISOTOPES

MEDIMOND srl

Lugar: Bologna, Italia; Año: 2005; p. 461 - 466

Abstract. In-phantom measurements of physical dose distributions are very important for BNCT planning validation. During exposure to thermal or epithermal neutrons, the absorbed dose in tissue is released by the various components of secondary radiation. Therefore, it is necessary to determine the spatial distributions of the absorbed dose, separating the various contributions due to each different secondary radiation produced by neutrons in tissue, because they have dissimilar biologic effect. The spatial trends of the different dose components and their relative contributions in each position depend on the beam geometry and also on the size and shape of the irradiated volume. It is therefore necessary to perform spatial determinations of each dose contribution, both in tumor and in healthy tissue. planning validation. During exposure to thermal or epithermal neutrons, the absorbed dose in tissue is released by the various components of secondary radiation. Therefore, it is necessary to determine the spatial distributions of the absorbed dose, separating the various contributions due to each different secondary radiation produced by neutrons in tissue, because they have dissimilar biologic effect. The spatial trends of the different dose components and their relative contributions in each position depend on the beam geometry and also on the size and shape of the irradiated volume. It is therefore necessary to perform spatial determinations of each dose contribution, both in tumor and in healthy tissue. planning validation. During exposure to thermal or epithermal neutrons, the absorbed dose in tissue is released by the various components of secondary radiation. Therefore, it is necessary to determine the spatial distributions of the absorbed dose, separating the various contributions due to each different secondary radiation produced by neutrons in tissue, because they have dissimilar biologic effect. The spatial trends of the different dose components and their relative contributions in each position depend on the beam geometry and also on the size and shape of the irradiated volume. It is therefore necessary to perform spatial determinations of each dose contribution, both in tumor and in healthy tissue. In-phantom measurements of physical dose distributions are very important for BNCT planning validation. During exposure to thermal or epithermal neutrons, the absorbed dose in tissue is released by the various components of secondary radiation. Therefore, it is necessary to determine the spatial distributions of the absorbed dose, separating the various contributions due to each different secondary radiation produced by neutrons in tissue, because they have dissimilar biologic effect. The spatial trends of the different dose components and their relative contributions in each position depend on the beam geometry and also on the size and shape of the irradiated volume. It is therefore necessary to perform spatial determinations of each dose contribution, both in tumor and in healthy tissue.