INVESTIGADORES
VALENTE Mauro Andres
artículos
Título:
SILVER NANOPARTICLES IN X-RAY BIOMEDICAL APPLICATIONS
Autor/es:
F. MATTEA; J. VEDELAGO; F. MALANO; C. GOMEZ; M. STRUMIA; M. VALENTE
Revista:
RADIATION PHYSICS AND CHEMISTRY (OXFORD)
Editorial:
PERGAMON-ELSEVIER SCIENCE LTD
Referencias:
Lugar: Amsterdam; Año: 2017 vol. 130 p. 442 - 450
ISSN:
0969-806X
Resumen:
The fluorescence of silver nanoparticles or ions can be used for detection and dose enhancementpurposes in X-ray irradiation applications. This study is focused on the full integration of the chemicalsynthesis of silver nanoparticles suitable for dosimetric and radiological purposes with characteristicsthat can be exploited in radiotherapy and radiodiagnostic. A narrow size distribution and a compatiblestabilizing agent is often desired in order to obtain homogeneous behaviors in nanoparticle suspension.With the method proposed in this study, nanoparticles ranging from 5 to 20 nm were obtained. Thefluorescence of aqueous suspensions of silver nanoparticles has been measured experimentally andsimulated with the Monte Carlo PENELOPE code for different silver concentrations and geometricalconfigurations. Finally, the feasibility of using these nanoparticles for the elaboration of Fricke geldosimeters has been tested obtaining a dose enhancement when compared with the same materialirradiated below the silver K-edge.
