PERSONAL DE APOYO
PALACIO Marcela Alejandra
artículos
Título:
Validation of a chiral HPLC assay for (R)-salbutamol sulfate
Autor/es:
ALEJANDRA HALABI; CARLOS FERRAYOLI; MARCELA PALACIO; VIVIANA DABBENE; SARA PALACIOS
Revista:
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
Editorial:
Elsevier
Referencias:
Año: 2004 p. 45 - 51
ISSN:
0731-7085
Resumen:
A fast, reliable and specific method for the screening, confirmation, determination and quantitation of salbutamol enantiomers
was developed and validated. The described procedure includes a single robust chiral HPLC determination employing a Teicoplanin
stationary phase. The method was evaluated for specificity, robustness, linearity, precision and accuracy. Under the
chromatographic conditions of the method, known impurities were separated from the active principle.
