INVESTIGADORES
FADER KAISER Claudio Marcelo
artículos
Título:
Role of VAMP7-Dependent Secretion of Reticulon 3 in Neurite Growth
Autor/es:
WOJNACKI, JOSÉ; NOLA, SÉBASTIEN; BUN, PHILIPPE; CHOLLEY, BÉATRICE; FILIPPINI, FRANCESCA; PRESSÉ, MARY T.; LIPECKA, JOANNA; MAN LAM, SIN; N'GUYEN, JULIE; SIMON, AXELLE; OUSLIMANI, AMINE; SHUI, GUANGHOU; FADER, CLAUDIO MARCELO; COLOMBO, MARIA ISABEL; GUERRERA, IDA CHIARA; GALLI, THIERRY
Revista:
Cell Reports
Editorial:
Elsevier B.V.
Referencias:
Año: 2020 vol. 33
Resumen:
VAMP7 is involved in exocytosis-mediated neurite growth and degradative autophagy. Using secretomics, Wojnacki et al. show that VAMP7 mediates the release of tubular ER-phagy receptor Reticulon 3, a secretory pathway greatly enhanced in autophagy-null neuronal cells. ER-phagy and unconventional secretion regulate neurite growth and polarization during nutrient deprivation.
