INVESTIGADORES
MOTRICH Ruben Dario
congresos y reuniones científicas
Título:
Functional differences in regulatory T cells from mice with different susceptibility to the development of autoimmune diseases.
Autor/es:
GODOY, GLORIA J.; SALAZAR, FLORENCIA C.; OLIVERA, CAROLINA; MOTRICH, RUBEN D.; RIVERO, VIRGINIA E.
Lugar:
Buenos Aires
Reunión:
Congreso; Reunión Conjunta de Sociedades de Biociencias.; 2017
Resumen:
NOD mice are characterized by their highly susceptibility to develop spontaneous and induced autoimmune diabetes, thyroiditis, sialiditis and prostatitis. It has been suggested that this increased susceptibility could be related to defects in the number and/or functionality in regulatory T cell (Treg) populations. In a previous work, we have shown that NOD mice exhibited significantly lower frequencies, absolute Treg numbers and mean fluorescence intensity (MFI) for Foxp3, when compared with other mice strains (p
