INVESTIGADORES
TONETTO Gabriela Marta
artículos
Título:
Burkholderia cepacia lipase: A versatile catalyst in synthesis reactions
Autor/es:
SANCHEZ D.; TONETTO G.; FERREIRA M.
Revista:
Biotechnology and Bioengineering
Editorial:
Wiley
Referencias:
Año: 2017 vol. 115 p. 6 - 24
ISSN:
1097-0290
Resumen:
The lipase from Burkholderia cepacia,formerly known as Pseudomonas cepacia lipase, is a commercial enzyme in bothsoluble and immobilized forms widely recognized for its thermal resistance andtolerance to a large number of solvents and short-chain alcohols. The mainapplications of this lipase are in transesterification reactions and in thesynthesis of drugs (because of the properties mentioned above). This review intendsto show the features of this enzyme and some of the most relevant aspects of its use in different synthesis reactions.Also, different immobilization techniques together with the effect of variouscompounds on lipase activity are presented. This lipase shows importantadvantages over other lipases, especially in reaction media including solventsor reactions involving short-chain alcohols.
