New carbon dots based on glycerol and urea and its application in the determination of tetracycline in urine samples

URIARTE, DAMIÁN; DOMINI, CLAUDIA; GARRIDO, MARIANO

TALANTA

ELSEVIER SCIENCE BV

Año: 2019 vol. 201 p. 143 - 148

0039-9140

The current study proposes a fast one-pot microwave assisted synthesis of new carbon dots (CDs) based on glycerol and urea. The novel carbon nanoparticles (GUCDs) have been appropriately characterized and exhibited good luminescent properties with a quantum yield of about 9.8%. Interestingly, the GUCDs are able to selectively interact with tetracycline class antibiotics, which produce a decrease in the native fluorescence of the CDs. On the base of these features, a new analytical method has been developed for the determination of tetracycline. The proposed method has shown satisfactory analytical parameters, such as good linearity range ?between 0.5 and 25 μM (R2 = 0.9997)? and an acceptable detection limit (165 nM). Moreover, the new method has been successfully applied for tetracycline determination in urine samples with good recoveries (94.7?103%) and precision (4.6 RSD%).