Potential adhesion ability to ephitelial cells of Saccharomyces cerevisiae mycotoxin adsorbents strain

ARMANDO M.R.; PIZZOLITTO R.P.; PEIRANO M.S.; SALVANO M.A.; ESCOBAR F.; SABINI L.; DALCERO A.; CAVAGLIERI L.R.

Tafi del Valle, Tucumán

Jornada; XXV Jornadas Científicas Organizadas Por La Asociación De Biología De Tucumán; 2008

Mycotoxins are toxic metabolites produced by fungi in feed. Their presence at levels above tolerable ones represents a threat to food safety and a significant risk for human and animal health. Some strategies have been developed to reduce mycotoxins contamination. One promising alternative is the use of functional foods containing probiotics capable of exerting beneficial effects on animals. Saccharomyces cerevisiae has been supplied as food by their huge profits and constitutes a potential tool for the removal of mycotoxins from animal feed. Adherence to epithelial cells is a prerequisite for temporarily persistence in the host and a key mechanism to carry out probiotic activity. The aim of this study was to determine the potential of S. cerevisiae strains for adherence to Vero cells. The S. cerevisiae strains used in this study were isolated from pig ecosystem and their ability for aflatoxin B1 and ochratoxin A detoxification was evaluated. The test was conducted following the methodology proposed by Kumura et al. (2004). The results indicate that the adherence ability of S. cerevisiae vary among strains. We observed adherence to Vero cells in 100% of the strains studied, RC009, RC012 and RC017 being the most highly adherent strains.