INVESTIGADORES
MARTINEZ CERON Maria Camila
artículos
Título:
Natural Snake Venom Inhibitors and their Pharmaceutical Uses: Challenges and Possibilities
Autor/es:
SOLEDAD L. SAAVEDRA; LUCÍA ÁVILA; SILVANA L. GIUDICESSI; FERNANDO ALBERICIO; SILVIA A. CAMPERI; OSVALDO CASCONE; MARÍA C. MARTÍNEZ CERON
Revista:
CURRENT PHARMACEUTICAL DESIGN.
Editorial:
BENTHAM SCIENCE PUBL LTD
Referencias:
Lugar: Oak Park; Año: 2018 vol. 24 p. 1737 - 1747
ISSN:
1381-6128
Resumen:
Nowadays, treatment with specific antivenins is considered the only cure for snakebites accidents. However,access to antivenom obstructs the successful implementation of the World Health Organization international guidelines. Inthe last few years, natural organic compounds, peptides and proteins with the ability to inhibit snake toxins and obtained from different sources such as plant extracts and animal blood have been proposed as antivenoms. In this work, we willfocus on the inhibitors of the main venom toxins, phospholipases A2 and metalloproteinases, and their application as novel antivenoms.
