INVESTIGADORES
POSTIGO Jose Alberto
libros
Título:
Late-Stage Fluorination of Bioactive Molecules and Biologically-Relevant Substrates
Autor/es:
A POSTIGO
Editorial:
Elsevier
Referencias:
Lugar: Oxford-ELSEVIER EDITORIAL; Año: 2018 p. 392
ISSN:
9780128129586
Resumen:
Paperback ISBN: 9780128129586eBook ISBN: 9780128130391Late Stage Fluorination of Bioactive Molecules and Biologically-Relevant Substrates reviews how the use of these techniques on compounds with already known and relevant biological activity can provide new pharmaceutical leads with improved medicinal properties. The fluorination strategies discussed take into account both conventional and novel reagents, including nucleophilic, electrophilic, those of a radical nature, and diverse families of organic compounds, such as (hetero) aromatic rings and aliphatic substrates. Drawing on the author?s expert knowledge, this book provides researchers with a broad set of applicable methods to use in their work.Key FeaturesHighlights the latest developments in the field in a concise volumeProvides details of key fluorinating reagents across diverse families of organic compoundsExplores the current applications and future potential of fluorine in drug development
