INVESTIGADORES
PAUTASSI Ricardo Marcos
congresos y reuniones científicas
Título:
Effect of open field exploration on frustration´s memory: Implications of the adrenergic system
Autor/es:
PSYRDELLIS M; PAUTASSI RM; MUSTACA A; JUSTEL N
Lugar:
Huerta Grande
Reunión:
Congreso; XXVIII Congreso Anual de la Sociedad Argentina de Investigación en Neurociencias; 2013
Institución organizadora:
Sociedad Argentina de Investigación en Neurociencias
Resumen:
When the subjects are exposed to a novel situation pre training or pre testing in a
specific learning situation, its retrieval is modulated(Izquierdo &
McGaugh,1985,1987).This phenomenon involves a complex series of
neurobiological and psychological mechanisms(Thiel,Huston &
Schwarting,1998).On the other hand,animals´ behavior depends on their previous
experience with different reward values.One way to study this phenomenon is with
the incentive downshift paradigm through the consummatory Successive Negative
Contrast.Thus, the aim of this work is to evaluate if the presentation of an open
field exposure disturbs the incentive downshift and the role of the noradrenergic
system in this phenomenon. For that purpose we submitted male rats to a 32%
sucrose solution and then it was change it to a 4% one.Previously to the first or
second contact with the downshifted sucrose solution the animals explored an
open field.The exposition to the field interfered with the aversive memory of the
event.Through the propranolol´s administration(an antagonist of the β-adrenergic
system)or a vehicle substance to the animals, given in trials 1 or 2 of the
devaluation phase, it was founded that this drug blocked the effect of open field. In
a theoretical level we want to understand the neurobiological processes involved
in emotional memory.The implications for the applied science are to provide
research to achieve better interventions for subjects who are vulnerable to loss
situations o deceptions.