Native Plants from Argentina Reported as Effective against Leishmania spp.

LOZANO, E; HAPON MB; CARGNELUTTI DIEGO; GAMARRA LUQUES CD,

BioMed Research Journal

SciTech Central Inc.

Lugar: California; Año: 2019 vol. 3 p. 65 - 68

2578-8892

Leishmaniasis represents a spectrum of diseases caused by infection with protozoan pathogens of the genus Leishmania. It isa major neglected tropical disease associated with high rates of disability and death, with extended endemic areas in theAmericas. Despite current therapeutic approaches, current treatments for leishmaniasis are unsatisfactory due to highassociated toxicity, cost, complex administration and the emergence of resistant strains. Because of this, efforts have greatlyincreased over the last decade to identify novel compounds with anti-leishmanial properties. Thus, one strategy in the searchfor new compounds is the screening of molecules purified from plant sources. The current work reviewed the availableinformation about the Argentinean natural sources reported as effective against Leishmania spp.; including: its relevantchemical compounds, efficiency and applied methodology. Reported studies need to be considered as precursors works toextend the search between the profuse native plants from Argentina.