INVESTIGADORES
HERKOVITS Jorge
artículos
Título:
lymphocyte populations in uterus drining lymph nodes at estrus and diestrus in Wistar rats
Autor/es:
COLOMBO, L.; LÓPEZ, M. HERKOVITS, J. AND ROUX, M
Revista:
AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY
Editorial:
mapu
Referencias:
Año: 1988 vol. 16 p. 143 - 145
ISSN:
8755-8920
Resumen:
Abstract
In this paper, data are presented on the characterization of uterus draining
lymph nodes (UDLN) B and T lymphocytes of virgin rats at estrus (E) and diestrus
(D). We established that the T/B lymphocyte relationship in the UDLN is less
than one at estrus and more than one at diestrus. This is due to a decrease in
the percentage and in the total number of mature T cell population in
association with a decrease in the percentage of the OX8 subset in the UDLN at
estrus. This situation may be related to an increase in estrogens known to
produce thymic involution. These changes were not observed when we studied
peripheral (popliteal) lymph nodes. The changes observed in the UDLN T cell
population at estrus could be under hormonal control and we think that this
condition may be important to prepare the immune system for an eventual
pregnancy.